Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 14/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503276 | 0.76 | EZH2 (0.57) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503338 | 0.76 | EZH2 (0.45) | EZH2HDAC1HDAC6 | |
| SCHEMBL19503908 | 0.76 | EZH2 (0.44) | EZH2HDAC1HDAC6PIK3CANPC1 | |
| SCHEMBL19503267 | 0.76 | EZH2 (0.71) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503495 | 0.72 | EZH2 (0.46) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503331 | 0.72 | EZH2 (0.46) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503339 | 0.72 | EZH2 (0.46) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503340 | 0.71 | EZH2 (0.47) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503335 | 0.71 | EZH2 (0.48) | EZH2HDAC1HDAC6EEDRBBP4 | |
| SCHEMBL19503336 | 0.71 | EZH2 (0.46) | EZH2HDAC1HDAC6EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184999-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-10-26 | — | — | WO | disclosed |