Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.74 |
| ▸ | BCL2 | P10415 | 3/20 | 0.69 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503775 | 0.98 | BCL2L1 (0.74) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3010491 | 0.91 | BCL2L1 (0.75) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3010487 | 0.91 | BCL2L1 (0.75) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL20992978 | 0.90 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL22566725 | 0.90 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL20759702 | 0.89 | BCL2L1 (0.71) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3002991 | 0.89 | BCL2L1 (0.71) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3002993 | 0.89 | BCL2L1 (0.71) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL20759757 | 0.89 | BCL2L1 (0.70) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL22566735 | 0.88 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184995-A1 | COMPOUNDS THAT INDUCE DEGRADATION OF ANTI-APOPTOTIC BCL-2 FAMILY PROTEINS AND THE USES THEREOF | BIOVENTURES, LLC (US) | 2017-10-26 | — | — | WO | disclosed |