Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 4/20 | 0.68 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19468773 | 0.98 | CHKA (0.71) | CHKAF2PRSS1KDM4AKDM2A | |
| SCHEMBL13905987 | 0.79 | CHKA (0.68) | CHKAF2PRSS1BCHEACHE | |
| SCHEMBL24511136 | 0.78 | F2 (0.69) | CHKAF2PRSS1MAOB | |
| Hydrochloric Acid SCHEMBL3954504 | 0.78 | CHKA (0.66) | CHKAF2PRSS1BCHEACHE | |
| Hydrochloric Acid SCHEMBL19468767 | 0.77 | F2 (0.67) | CHKAF2PRSS1MAOB | |
| Bromide SCHEMBL22412976 | 0.77 | CHKA (0.70) | CHKAF2PRSS1MAOBACHE | |
| SCHEMBL9330100 | 0.75 | KDM4A (0.45) | CHKAKDM4AKDM2ALOXL2BCHE | |
| SCHEMBL18459220 | 0.74 | CHKA (0.61) | CHKAF2PRSS1MAOBLOXL2 | |
| SCHEMBL10692064 | 0.74 | CHKA (0.57) | CHKAF2PRSS1ACHE | |
| Bromide SCHEMBL10916294 | 0.73 | CHKA (0.46) | CHKAKDM4AKDM2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305861-A1 | HETEROARYL COMPOUNDS COMPRISING NITROGEN AND USE THEREOF | IMMUNOMET THERAPEUTICS, INC (US) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305861-A1 | HETEROARYL COMPOUNDS COMPRISING NITROGEN AND USE THEREOF | MKI67, NUDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CHKA 1724/4885F2 1398/4885PRSS1 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.