Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 16/20 | 0.51 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19468696 | 0.99 | CHKA (0.50) | CHKACHKBBCHEACHEAGXT | |
| SCHEMBL19504080 | 0.97 | CHKA (0.48) | CHKACHKBBCHEACHEAGXT | |
| Hydrochloric Acid SCHEMBL19468881 | 0.96 | CHKA (0.47) | CHKACHKBBCHEACHEAGXT | |
| SCHEMBL19504369 | 0.84 | CHKA (0.52) | CHKACHKBBCHEACHEAGXT | |
| Hydrochloric Acid SCHEMBL19468769 | 0.82 | CHKA (0.51) | CHKACHKBBCHEACHEAGXT | |
| SCHEMBL19504948 | 0.81 | CHKA (0.49) | CHKACHKBBCHEACHEAGXT | |
| Hydrochloric Acid SCHEMBL19468961 | 0.80 | CHKA (0.48) | CHKACHKBBCHEACHEAGXT | |
| SCHEMBL19497622 | 0.76 | CHKA (0.59) | CHKACHKBBCHEACHEAGXT | |
| Hydrochloric Acid SCHEMBL19468808 | 0.75 | CHKA (0.57) | CHKACHKBBCHEACHEAGXT | |
| Hydrochloric Acid SCHEMBL19468895 | 0.75 | F2 (0.39) | CHKAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305861-A1 | HETEROARYL COMPOUNDS COMPRISING NITROGEN AND USE THEREOF | IMMUNOMET THERAPEUTICS, INC (US) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305861-A1 | HETEROARYL COMPOUNDS COMPRISING NITROGEN AND USE THEREOF | MKI67, NUDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CHKA 1724/4885CHKB 1480/4885BCHE 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.