SCHEMBL19508730

SCHEMBL19508730

CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)NC1CCC(OC(=O)C2(C)COC(=O)OC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18256743 1.00 GAA (0.31) GAANFKB1NFKB2RELA
SCHEMBL19508957 0.84 EPHX1 (0.34) GAANFKB1NFKB2RELA
SCHEMBL18257756 0.84 GAA (0.33) GAANFKB1NFKB2RELA
SCHEMBL20982174 0.79 GAA (0.31) GAA
SCHEMBL12629708 0.76 IDO1 (0.32)
SCHEMBL18257736 0.76 IDO1 (0.32)
SCHEMBL18258074 0.75 SERPINE1 (0.34)
SCHEMBL19508986 0.74 GAA (0.39) GAANFKB1NFKB2RELA
SCHEMBL18256753 0.74 GAA (0.39) GAANFKB1NFKB2RELA
SCHEMBL20982162 0.74 CA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2021-04-20 US disclosed
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC. (US) 2020-09-22 US disclosed
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS PUF60, CAPG, GMPS GAA 966/4885NFKB1 3926/4885NFKB2 4128/4885
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS GAA 966/4885NFKB1 3926/4885NFKB2 4128/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS GAA 966/4885NFKB1 3926/4885NFKB2 4128/4885
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS GAA 966/4885NFKB1 3926/4885NFKB2 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.