SCHEMBL19508979

SCHEMBL19508979

FC(F)(F)c1cc(NC(=S)Nc2cc#ccc2)cc(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.54
KDM4E B2RXH2 3/20 0.54
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MYC P01106 1/20 0.49
MAX P61244 1/20 0.49
ALDH1A1 P00352 6/20 0.45
NPSR1 Q6W5P4 4/20 0.45
GAA P10253 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
IDO1 P14902 1/20 0.43
TEK Q02763 1/20 0.43
P2RX1 P51575 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7569356 0.83 MAPT (0.57) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL11009249 0.82 MAPT (0.67) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL10221543 0.76 MAPT (0.69) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL22567749 0.74 MAPT (0.78) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL4555022 0.73 MAPT (0.67) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL4554273 0.73 MAPT (0.67) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL6815679 0.73 MAPT (0.61) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL12404443 0.72 SMN1; SMN2 (0.71) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL15481298 0.72 MAPT (0.56) MAPTKDM4EMEN1KMT2AMYC
SCHEMBL10133740 0.72 MAPT (0.62) MAPTKDM4EMEN1KMT2AMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC. (US) 2020-09-22 US disclosed
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS PUF60, CAPG, GMPS MAPT 1608/4885KDM4E 3543/4885MEN1 2821/4885
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS MAPT 1608/4885KDM4E 3543/4885MEN1 2821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.