Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 11/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475320 | 0.83 | KMT2A (0.74) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475347 | 0.82 | MOK (1.00) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475498 | 0.82 | KMT2A (0.85) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL5154506 | 0.82 | KDM4E (1.00) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475306 | 0.80 | MOK (1.00) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL17308322 | 0.80 | KMT2A (0.81) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL16603957 | 0.79 | KMT2A (1.00) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475480 | 0.78 | MOK (1.00) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475453 | 0.77 | MOK (0.77) | MOKKMT2AKDM4EPDE10AMEN1 | |
| SCHEMBL19475332 | 0.76 | MOK (0.84) | MOKKMT2AKDM4EPDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184547-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2017-10-26 | — | — | WO | disclosed |