Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 5/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.55 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.55 |
| ▸ | CHRNG | P07510 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195154 | 1.00 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL29376765 | 1.00 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Hydrochloric Acid SCHEMBL29615758 | 0.98 | CHRNA7 (0.97) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL4785907 | 0.94 | CHRNA7 (0.88) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL4786027 | 0.90 | CHRNA7 (0.82) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL29733346 | 0.88 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL372800 | 0.88 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL5389874 | 0.88 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL5378467 | 0.88 | CHRNA7 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Hydrochloric Acid SCHEMBL5378422 | 0.87 | CHRNA7 (0.97) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134395-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | Duke University (US) | 2009-12-23 | — | — | EP | claimed |
| WO-2008121610-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | DUKE UNIVERSITY (US) | 2008-10-09 | — | — | WO | claimed |
| US-20080241255-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | DUKE UNIVERSITY (US) | 2008-10-02 | — | — | US | claimed |
| EP-1074256-A2 | Depolarizing skeletal muscle relaxants | R.J. REYNOLDS TOBACCO COMPANY (US) | 2001-02-07 | — | — | EP | claimed |
| EP-0804195-A2 | DEPOLARIZING SKELETAL MUSCLE RELAXANTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1997-11-05 | — | — | EP | claimed |
| US-5510355-A | ADMINISTERING 2-(3-PYRIDYL)-QUINUCLILIDINE DERIVATIVE TO THE PATIENT UNDERGOING SURGICAL PROCEDURE REQUIRING ANESTHESIA AS A MUSCLE RELEXANT | TARGACEPT, INC., A CORPORATION OF DELAWARE | 1996-04-23 | — | — | US | claimed |
| WO-1996007410-A2 | DEPOLARIZING SKELETAL MUSCLE RELAXANTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1996-03-14 | — | — | WO | claimed |
| US-12310404-B2 | Aerosol-generating system comprising integrated piercing element | PHILIP MORRIS PRODUCTS S.A. (CH) | 2025-05-27 | — | — | US | disclosed |
| CN-118666833-B | Preparation method of 2- (5-bromopyridine-3-yl) quinuclidine | 龙曦宁（上海）医药科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118666833-A | Preparation method of 2- (5-bromopyridine-3-yl) quinuclidine | 龙曦宁（上海）医药科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-112656038-B | Resealable aerosol-generating article | 菲利普莫里斯生产公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112716051-B | Aerosol generating system comprising a ruptured portion | 菲利普莫里斯生产公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11805809-B2 | Aerosol-generating system comprising a rupturing portion | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-11-07 | — | — | US | disclosed |
| US-5559124-A | QUINUCLIDINE DERIVATIVE | TARGACEPT, INC., A CORPORATION OF DELAWARE | 1996-09-24 | — | — | US | disclosed |
| WO-1996007410-A3 | DEPOLARIZING SKELETAL MUSCLE RELAXANTS | REYNOLDS TOBACCO CO R (US) | 1996-05-30 | — | — | WO | disclosed |
| US-5510355-A | ADMINISTERING 2-(3-PYRIDYL)-QUINUCLILIDINE DERIVATIVE TO THE PATIENT UNDERGOING SURGICAL PROCEDURE REQUIRING ANESTHESIA AS A MUSCLE RELEXANT | TARGACEPT, INC., A CORPORATION OF DELAWARE | 1996-04-23 | — | — | US | disclosed |
| US-5510355-A | ADMINISTERING 2-(3-PYRIDYL)-QUINUCLILIDINE DERIVATIVE TO THE PATIENT UNDERGOING SURGICAL PROCEDURE REQUIRING ANESTHESIA AS A MUSCLE RELEXANT | TARGACEPT, INC., A CORPORATION OF DELAWARE | 1996-04-23 | — | — | US | disclosed |
| WO-1996007410-A2 | DEPOLARIZING SKELETAL MUSCLE RELAXANTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1996007410-A2 | DEPOLARIZING SKELETAL MUSCLE RELAXANTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1995003306-A1 | ARTHROPODICIDAL AZACYCLIC HETEROCYCLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-02 | — | — | WO | disclosed |