Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831366 | 0.83 | LARS1 (0.60) | LARS1HTR2AHTR2CHTR2B | |
| SCHEMBL16256484 | 0.83 | LARS1 (0.47) | LARS1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL13035602 | 0.83 | LARS1 (0.60) | LARS1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3446383 | 0.82 | LARS1 (0.61) | LARS1HTR2AHTR2CHTR2B | |
| SCHEMBL20482071 | 0.78 | LARS1 (0.43) | LARS1 | |
| SCHEMBL20481923 | 0.78 | LARS1 (0.43) | LARS1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL20481959 | 0.78 | LARS1 (0.43) | LARS1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL20481916 | 0.77 | LARS1 (0.42) | LARS1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL3446061 | 0.76 | LARS1 (0.41) | LARS1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL20481966 | 0.76 | LARS1 (0.41) | LARS1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796735-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |