SCHEMBL19542307

SCHEMBL19542307

CCCCN(CCSSc1ccccn1)C(=O)CC[C@H]1C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)N[C@@H](Cc2ccccc2)C(=O)N1C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 16/20 0.43
▸ SSTR5 P35346 14/20 0.41
▸ SSTR1 P30872 13/20 0.41
▸ SSTR3 P32745 13/20 0.41
▸ SSTR4 P31391 11/20 0.41
▸ DRD2 P14416 1/20 0.37
▸ PDCD1 Q15116 1/20 0.37
▸ CD274 Q9NZQ7 1/20 0.37
▸ ROR1 Q01973 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17404774 0.93 SSTR2 (0.48) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL18712401 0.89 SSTR2 (0.42) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL19308237 0.85 SSTR2 (0.45) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL18712573 0.83 SSTR2 (0.45) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL21892070 0.78 SSTR2 (0.52) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL17404629 0.78 SSTR2 (0.52) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL29897024 0.77 SSTR2 (0.59) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL17404627 0.77 SSTR2 (0.59) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL19543819 0.76 SSTR2 (0.59) SSTR2SSTR5SSTR1SSTR3SSTR4
SCHEMBL18359782 0.75 SSTR2 (0.58) SSTR2SSTR5SSTR1SSTR3SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170312245-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2017-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170312245-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR5, SSTR1, SSTR4 SSTR2 4/4885SSTR5 1/4885SSTR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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