SCHEMBL1954404

SCHEMBL1954404

C=CCCC/C=C(/C)N(C)CCC=C(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10791258 0.83 MAPT (0.43) ABCC4MAPT
SCHEMBL23829765 0.83 MAPT (0.43) ABCC4MAPT
SCHEMBL460316 0.82 ABCC4 (0.31) ABCC4MAPT
SCHEMBL9643683 0.80 MAPT (0.48) ABCC4MAPT
SCHEMBL9643673 0.80 MAPT (0.48) ABCC4MAPT
SCHEMBL9463894 0.78 MAPT (0.52) ABCC4MAPT
SCHEMBL9463901 0.78 MAPT (0.52) ABCC4MAPT
SCHEMBL1841996 0.78 MAPT (0.52) ABCC4MAPT
SCHEMBL26098086 0.78 MAPT (0.52) ABCC4MAPT
SCHEMBL26098646 0.78 MAPT (0.52) ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 ABCC4 2965/4885MAPT 3113/4885TDP1 3525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.