Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.47 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544718 | 0.88 | BTK (0.55) | BTK | |
| SCHEMBL19544611 | 0.87 | BTK (0.59) | BTK | |
| SCHEMBL19544568 | 0.87 | BTK (0.59) | BTK | |
| SCHEMBL15472786 | 0.86 | BTK (0.57) | BTK | |
| SCHEMBL19544659 | 0.86 | BTK (0.55) | BTK | |
| SCHEMBL19544647 | 0.86 | BTK (0.55) | BTK | |
| SCHEMBL19544728 | 0.85 | BTK (0.54) | BTK | |
| SCHEMBL25060339 | 0.85 | BTK (0.43) | BTK | |
| SCHEMBL19624990 | 0.81 | BTK (0.43) | BTK | |
| SCHEMBL19544474 | 0.81 | BTK (0.43) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | BTK 1/4885KRAS 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.