Theaflavin

Theaflavin

SCHEMBL19551

O=c1c(O)cc([C@H]2Oc3cc(O)cc(O)c3C[C@H]2O)cc2c([C@H]3Oc4cc(O)cc(O)c4C[C@H]3O)cc(O)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 1.00
MAPT P10636 5/20 1.00
APEX1 P27695 5/20 1.00
RECQL P46063 5/20 1.00
HSD17B10 Q99714 5/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
HPGD P15428 4/20 1.00
ALOX15 P16050 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
CYP3A4 P08684 4/20 1.00
BLM P54132 3/20 1.00
USP2 O75604 2/20 1.00
THRB P10828 2/20 1.00
CASP1 P29466 2/20 1.00
GALK1 P51570 2/20 1.00
BCL2 P10415 3/20 0.81
CYP17A1 P05093 1/20 0.81
CDK2 P24941 1/20 0.81
BACE1 P56817 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Theaflavin SCHEMBL4379393 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL29373772 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL13530895 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL18346731 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL13300889 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL12658747 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL14847403 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL17430775 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL12792925 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10
Theaflavin SCHEMBL29779739 1.00 KDM4E (1.00) KDM4EMAPTAPEX1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121321258-B Multifunctional cellulose-based fiber and preparation method thereof QINGDAO UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122081429-A Method for alternately catalyzing and improving theaflavin yield by using exogenous enzyme 2026-05-26 CN claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
CN-122056317-A Yang Shusang yellow fermented tea and preparation method and application thereof 湖南农业大学 2026-05-19 CN claimed
CN-122030385-A Theaflavin liquid and its preparation method and application 广州瑞丰生物科技有限公司 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
CN-122004484-A Method for synergistically increasing resistant starch by autoclave treatment and polyphenol 湖南农业大学 2026-05-12 CN claimed
US-12582592-B2 Flavor or aroma deterioration inhibitor containing theanaphthoquinone and analogues thereof as active ingredient OGAWA & CO., LTD. (JP) 2026-03-24 US claimed
CN-121569859-A Dried orange peel black tea and preparation method thereof 广东省农业科学院茶叶研究所 2026-02-27 CN claimed
CN-121569857-A Preparation method of high-activity theaflavin 江苏德和生物科技有限公司 2026-02-27 CN claimed
US-5135957-A Tea polyphenols; applying catechin compounds; fungicides MITSUI NORIN CO., LTD. (JP) 1992-08-04 US claimed
US-5104901-A Orally administering tea polyphenol; theaflavin, catechin, epigallocatechin gallate MITSUI NORIN CO., LTD. (JP) 1992-04-14 US claimed
EP-0443090-A2 Agent for preventing infection with methicillin-resistant staphylococcus MITSUI NORIN CO., LTD. (JP) 1991-08-28 EP claimed
EP-0423419-A1 Inhibitive agent against activity of alpha-amylase MITSUI NORIN CO., LTD. (JP) 1991-04-24 EP claimed
EP-0417385-A2 Preventive and curative medicament against infection with influenza virus, containing tea or tea polyphenols MITSUI NORIN CO., LTD. (JP) 1991-03-20 EP claimed
EP-0415126-A1 Anti-dental plaque agents MITSUI NORIN CO., LTD. (JP) 1991-03-06 EP claimed
EP-0397914-A1 Antitoxins for bacterial exotoxins MITSUI NORIN CO., LTD. (JP) 1990-11-22 EP claimed
US-4840966-A ADMINISTERING EPIGALLOCATECHIN GALLATE, THEAFLAVIN. THEAFLAVIN MONO(DI)GALLATE MITSUI NORIN CO., LTD. (JP) 1989-06-20 US claimed
US-4748033-A Tea concentrate having freeze thaw stability and enhanced cold water solubility THE PROCTER & GAMBLE COMPANY (US) 1988-05-31 US claimed
US-4105784-A THEAFLAVIN AND DERIVATIVES DIRECTOR OF NATIONAL RESEARCH INSTITUTE OF TEA (JP) 1978-08-08 US claimed