Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | RAC1 | P63000 | 3/20 | 0.36 |
| ▸ | CDC42 | P60953 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATP2A1 | O14983 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129965 | 0.89 | PDE4A (0.39) | MAPTCYP3A4IDO1TDO2ACACA | |
| SCHEMBL179696 | 0.83 | MAPT (0.46) | MAPTCYP3A4CTDSP1IDO1TDO2 | |
| SCHEMBL128940 | 0.79 | MAPT (0.42) | MAPTCYP3A4CTDSP1IDO1TDO2 | |
| SCHEMBL195313 | 0.79 | IDO1 (0.37) | MAPTCYP3A4CTDSP1IDO1TDO2 | |
| SCHEMBL129668 | 0.76 | PDE3B (0.48) | MAPTCYP3A4PDE5APDE4APDE1A | |
| SCHEMBL7821022 | 0.71 | MAPT (0.65) | MAPTCYP3A4IDO1TDO2RAD52 | |
| SCHEMBL13284349 | 0.70 | RAC1 (0.53) | MAPTCYP3A4CTDSP1IDO1TDO2 | |
| SCHEMBL129945 | 0.70 | GAA (0.35) | MAPTCYP3A4IDO1TDO2ALDH1A1 | |
| SCHEMBL13284346 | 0.70 | RAC1 (0.52) | MAPTCYP3A4CTDSP1IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL7812760 | 0.70 | MAPT (0.64) | MAPTCYP3A4IDO1TDO2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | MAPT 4740/4885CYP3A4 464/4885CTDSP1 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.