Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424917 | 0.93 | KDM4E (0.74) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL24325073 | 0.87 | KDM4E (0.60) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL6109360 | 0.86 | GAA (0.66) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL195591 | 0.85 | KDM4E (0.61) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL372600 | 0.85 | KDM4E (1.00) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL31408659 | 0.85 | KDM4E (1.00) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL19554326 | 0.84 | KDM4E (0.51) | KDM4EGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL22833382 | 0.84 | KDM4E (0.57) | KDM4EGAAALDH1A1POLBCFTR | |
| SCHEMBL17700427 | 0.84 | KDM4E (0.50) | KDM4EGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL2900514 | 0.84 | KDM4E (0.59) | KDM4EGAAALDH1A1POLBCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755331-B1 | AGONISTS OF STIMULATOR OF INTERFERON GENES (STING) FOR USE IN THE TREATMENT OF CANCER | SCRIPPS RESEARCH INST (US) | 2026-01-28 | — | — | EP | disclosed |
| CN-111971045-B | Agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-117942342-A | Agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2024-04-30 | — | — | CN | disclosed |
| US-11701364-B2 | Agonists of stimulator of interferon genes sting | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-18 | — | — | US | disclosed |
| US-11701364-B2 | Agonists of stimulator of interferon genes sting | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-18 | — | — | US | disclosed |
| EP-3733663-B1 | 1-[6-[[4-(PHENYLAMINO)-6-QUINAZOLINYL]OXY]-3-AZABICYCLO[3.1.1]HEPT-3-YL]-2-PROPEN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS IRREVERSIBLE INHIBITORS OF PAN-HER TYROSINE KINASE FOR THE TREATMENT OF CANCER | CHENGDU JINRUI FOUND BIOTECH CO LTD (CN) | 2023-05-17 | — | — | EP | disclosed |
| US-20210205321-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2021-07-08 | — | — | US | disclosed |
| US-20210205321-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2021-07-08 | — | — | US | disclosed |
| US-20210078958-A1 | QUINAZOLINE DERIVATIVE AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3755331-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | The Scripps Research Institute (US) | 2020-12-30 | — | — | EP | disclosed |
| CN-111971045-A | Agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2020-11-20 | — | — | CN | disclosed |
| EP-3733663-A1 | QUINAZOLINE DERIVATIVE AND USE THEREOF | Medshine Discovery Inc. (CN) | 2020-11-04 | — | — | EP | disclosed |
| WO-2019165032-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-08-29 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205321-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | STING1, IRF3, IFNAR1 | KDM4E 1741/4885GAA 894/4885ALDH1A1 3626/4885 |
| US-11701364-B2 | Agonists of stimulator of interferon genes sting | STING1, IRF3, IFNAR1 | KDM4E 1741/4885GAA 894/4885ALDH1A1 3626/4885 |
| US-20210078958-A1 | QUINAZOLINE DERIVATIVE AND USE THEREOF | ABL1, ERBB2, FLT3 | KDM4E 1667/4885GAA 1286/4885ALDH1A1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.