Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554163 | 0.87 | SERPINE1 (0.60) | SERPINE1ABCG2TMPRSS4KDRMAPT | |
| SCHEMBL23258455 | 0.87 | ABCG2 (0.62) | ABCG2ABCB1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL419421 | 0.87 | SERPINE1 (0.78) | SERPINE1TMPRSS4MAPTAKR1C4AKR1C3 | |
| SCHEMBL6708107 | 0.80 | F10 (0.56) | SERPINE1HPGDHSD17B10KDRNPC1 | |
| SCHEMBL417156 | 0.79 | SERPINE1 (0.61) | SERPINE1ABCG2ABCB1NPC1RAB9A | |
| SCHEMBL419380 | 0.78 | CYSLTR1 (0.57) | SERPINE1 | |
| SCHEMBL4204619 | 0.77 | CNR2 (0.66) | SERPINE1ABCB1TMPRSS4NPC1CYP3A4 | |
| SCHEMBL31306457 | 0.77 | GAA (0.53) | SERPINE1TMPRSS4ALDH1A1KDM4EKDR | |
| SCHEMBL21446739 | 0.76 | NPC1 (0.60) | ABCG2ABCB1ALDH1A1HPGDKDM4E | |
| SCHEMBL418778 | 0.76 | CYSLTR1 (0.68) | ALDH1A1KDM4EHSD17B10NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |