Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21857652 | 0.88 | GAA (0.42) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL2012660 | 0.84 | CA12 (0.41) | KDM4EGAAABL1NQO2TSHR | |
| SCHEMBL23015343 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL149267 | 0.83 | GAA (0.44) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL29511129 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL2391826 | 0.77 | CFTR (0.58) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL1884944 | 0.77 | GAA (0.64) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL30344983 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1GAAABL1HSD17B10 | |
| SCHEMBL28183743 | 0.76 | ABL1 (0.38) | KDM4EALDH1A1GAAABL1HPGD | |
| SCHEMBL25156545 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1GAAABL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |