Benzoxazolinone

Benzoxazolinone

SCHEMBL19555

O=c1[nH]c2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGT O15294 1/20 1.00
F2 P00734 1/20 0.57
CFD P00746 1/20 0.57
KDM4E B2RXH2 4/20 0.56
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
PSMB8 P28062 1/20 0.56
NOS1 P29475 4/20 0.53
NOS3 P29474 3/20 0.53
NOS2 P35228 3/20 0.53
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
ADRA2A P08913 1/20 0.53
TSHR P16473 1/20 0.53
THPO P40225 1/20 0.53
BLM P54132 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
KMO O15229 1/20 0.47
IL4I1 Q96RQ9 1/20 0.46
PDE3B Q13370 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoxazolinone SCHEMBL29475399 1.00 OGT (1.00) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL3927631 1.00 OGT (1.00) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL9110846 1.00 OGT (1.00) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL3650873 0.98 OGT (0.95) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL28920994 0.98 OGT (0.95) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL28598217 0.98 OGT (0.95) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL6689592 0.94 OGT (0.88) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL29227403 0.92 OGT (0.84) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL385987 0.90 OGT (0.81) OGTF2CFDKDM4EALDH1A1
Benzoxazolinone SCHEMBL17260632 0.90 OGT (0.81) OGTF2CFDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10862 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIV DE MONTREAL (CA) 2026-05-21 US claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
EP-3856178-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 EP claimed
US-20260015445-A1 COPOLYMER, PIEZOELECTRIC MATERIAL, PIEZOELECTRIC FILM, AND PIEZOELECTRIC ELEMENT TDK CORPORATION (JP) 2026-01-15 US claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
WO-2025264581-A1 P110 INHIBITORS FOR THE TREATMENT OF CANCER LEAPFROG BIO, INC. (US) 2025-12-26 WO claimed
EP-4143179-B1 AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER IDORSIA PHARMACEUTICALS LTD (CH) 2025-10-22 EP claimed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
EP-4602047-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF The Universite de Montreal (CA) 2025-08-20 EP claimed
WO-2025129023-A1 INDOLE AMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2025-06-19 WO claimed
US-4309549-A Benzoxazolone preparation RHONE-POULENC AGROCHIMIE (FR) 1982-01-05 US claimed
US-4294912-A INCLUDING A SECOND DESTABILIZER; COLOR FILMS EASTMAN KODAK COMPANY (US) 1981-10-13 US claimed
EP-0037352-A1 Process for the preparation of chlorinated benzoxazolone derivatives RHONE-POULENC AGROCHIMIE (FR) 1981-10-07 EP claimed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US claimed
EP-0022041-A1 Process for the preparation of benzoxazolone RHONE-POULENC AGROCHIMIE (FR) 1981-01-07 EP claimed
EP-0020281-A1 Preparation of benzoxazolone RHONE-POULENC AGROCHIMIE (FR) 1980-12-10 EP claimed
EP-0018931-A1 Preparation of benzoxazolone RHONE-POULENC AGROCHIMIE (FR) 1980-11-12 EP claimed
US-4191703-A REACTING 5- OR 6-(HYDROXYETHYL SULFONYL) BENZOXAZOL-2- ONE WITH SULFURIC ACID AND/OR SULFUR TRIOXIDE WHILE KNEADING HOECHST AKTIENGESELLSCHAFT (DE) 1980-03-04 US claimed
US-4169091-A Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-25 US claimed
US-4128558-A FIREPROOFING BAYER AKTIENGESELLSCHAFT (DE) 1978-12-05 US claimed