SCHEMBL1955830

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2532235	0.89	TSHR (0.54)	TSHRL3MBTL1MAPTPOLBERN1
	SCHEMBL1958493	0.88	TSHR (0.50)	KDM4ECYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL1956268	0.85	TSHR (0.47)	KDM4ENPSR1TSHRHTTMAPT
	SCHEMBL1958658	0.85	TSHR (0.47)	KDM4ECYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL1742275	0.85	SMN1; SMN2 (0.51)	KDM4ECYP1A2CYP2C9CYP2C19NPSR1
	SCHEMBL4502266	0.84	TTR (0.53)	KDM4ECYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL1959329	0.83	GAA (0.51)	KDM4ETSHRL3MBTL1MAPTPOLB
	SCHEMBL2478839	0.83	TSHR (0.46)	KDM4ECYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL1960348	0.82	TSHR (0.50)	KDM4ECYP1A2CYP2C9CYP2C19NPSR1
	SCHEMBL1958330	0.82	CA12 (0.48)	KDM4ENPSR1TSHRMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.