Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928374 | 0.85 | PPARG (0.48) | PPARGFFAR1PPARA | |
| SCHEMBL14213652 | 0.84 | PPARG (0.33) | PPARGFFAR1PPARAESR1 | |
| SCHEMBL14299359 | 0.76 | FFAR1 (0.32) | PPARGFFAR1PPARAESR1 | |
| SCHEMBL19217703 | 0.73 | FFAR1 (0.33) | PPARGFFAR1 | |
| SCHEMBL19559735 | 0.69 | PPARG (0.38) | PPARGFFAR1PPARAESR1 | |
| SCHEMBL19559694 | 0.69 | PPARG (0.38) | PPARGFFAR1PPARAESR1 | |
| SCHEMBL19217777 | 0.68 | PPARG (0.40) | PPARGFFAR1 | |
| SCHEMBL19559726 | 0.68 | PPARG (0.49) | PPARGFFAR1 | |
| SCHEMBL19559692 | 0.67 | FFAR1 (0.41) | PPARGFFAR1ESR1 | |
| SCHEMBL19559754 | 0.67 | FFAR1 (0.41) | PPARGFFAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513070-B1 | PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES | CIRIUS THERAPEUTICS INC (US) | 2017-11-08 | — | — | EP | disclosed |