Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559693 | 0.89 | PPARG (0.41) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559659 | 0.89 | PPARG (0.41) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559778 | 0.88 | PPARG (0.38) | PPARGFFAR1CYP2C9MAOBMCL1 | |
| SCHEMBL19217570 | 0.88 | PPARG (0.68) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559754 | 0.87 | FFAR1 (0.41) | PPARGFFAR1CYP2C9MCL1 | |
| SCHEMBL19559692 | 0.87 | FFAR1 (0.41) | PPARGFFAR1CYP2C9MCL1 | |
| SCHEMBL19559701 | 0.84 | PPARG (0.51) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559694 | 0.83 | PPARG (0.38) | PPARGFFAR1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL19559735 | 0.83 | PPARG (0.38) | PPARGFFAR1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL19559787 | 0.82 | PPARG (0.50) | PPARGFFAR1MPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513070-B1 | PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES | CIRIUS THERAPEUTICS INC (US) | 2017-11-08 | — | — | EP | disclosed |