Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560856 | 0.94 | PDE10A (0.63) | PDE10A | |
| SCHEMBL19560794 | 0.79 | PDE10A (0.61) | PDE10A | |
| SCHEMBL19560784 | 0.79 | PDE10A (0.53) | PDE10A | |
| SCHEMBL15551807 | 0.78 | PDE10A (1.00) | PDE10A | |
| SCHEMBL19560788 | 0.76 | PDE10A (0.60) | PDE10A | |
| SCHEMBL19560989 | 0.75 | PDE10A (0.61) | PDE10A | |
| SCHEMBL15549793 | 0.73 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15549617 | 0.71 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15538187 | 0.70 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15538099 | 0.69 | PDE10A (0.78) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855455-B1 | TRIAZOLO COMPOUNDS AS PDE10 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-11-08 | — | — | EP | disclosed |