Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867689 | 1.00 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868292 | 0.89 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868298 | 0.87 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868307 | 0.86 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16867811 | 0.86 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868293 | 0.85 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868246 | 0.85 | PDE2A (1.00) | PDE2A | |
| SCHEMBL18388241 | 0.85 | PDE2A (1.00) | PDE2A | |
| SCHEMBL16868037 | 0.83 | PDE2A (1.00) | PDE2A | |
| SCHEMBL20494180 | 0.82 | PDE2A (1.00) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815796-B2 | Pyrimidone carboxamide compounds as PDE2 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-11-14 | — | — | US | claimed |