SCHEMBL19575433

SCHEMBL19575433

CC(C)N1CCCC(OC2=CC=C(Cl)C=CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24742927 0.65 HRH3 (0.41) HRH3
SCHEMBL10057696 0.64 HRH3 (0.66) HRH3
SCHEMBL21191907 0.63 HRH3 (0.40) HRH3
SCHEMBL21945955 0.63 POLB (0.30)
SCHEMBL19575422 0.62 HRH3 (0.66) HRH3
SCHEMBL21191798 0.61 HRH3 (0.42) HRH3
SCHEMBL19633495 0.61 HRH3 (0.66) HRH3
SCHEMBL8025279 0.60 HRH3 (0.69) HRH3
SCHEMBL13898673 0.60 HRH3 (0.53) HRH3
SCHEMBL20069052 0.60 HRH3 (0.56) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017191599-A1 SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES GENOSCIENCE PHARMA (FR) 2017-11-09 WO disclosed