Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 18/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716965 | 0.91 | P2RX4 (0.56) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL19552372 | 0.91 | P2RX4 (0.56) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL19576956 | 0.83 | P2RX4 (0.49) | P2RX4KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL22353219 | 0.83 | P2RX4 (0.42) | P2RX4 | |
| SCHEMBL20561849 | 0.82 | P2RX4 (0.56) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL19576993 | 0.82 | P2RX4 (0.49) | P2RX4KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19576529 | 0.81 | P2RX4 (0.47) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL19576998 | 0.80 | P2RX4 (0.47) | P2RX4KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19551474 | 0.79 | P2RX4 (0.53) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL29716839 | 0.79 | P2RX4 (0.53) | P2RX4KCNJ6KCNJ5KCNJ3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |
| WO-2017191000-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | WO | disclosed |