Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 5/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46483 | 0.96 | SLC34A2 (0.55) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL19580040 | 0.94 | SLC34A2 (0.55) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL19579940 | 0.92 | SLC34A2 (0.58) | SLC34A2BRAFRAF1KDM4EUSP2 | |
| SCHEMBL45535 | 0.91 | SLC34A2 (0.64) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL19580017 | 0.91 | SLC34A2 (0.57) | SLC34A2BRAFRAF1KDM4EUSP2 | |
| SCHEMBL19579956 | 0.90 | SLC34A2 (0.57) | SLC34A2BRAFRAF1KDM4EUSP2 | |
| SCHEMBL19579976 | 0.90 | SLC34A2 (0.63) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL5999719 | 0.90 | SLC34A2 (0.65) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL39722 | 0.90 | SLC34A2 (0.57) | SLC34A2BRAFRAF1KDM4ELMNA | |
| SCHEMBL6002472 | 0.89 | SLC34A2 (0.55) | SLC34A2BRAFRAF1KDM4EROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |