Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 5/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002472 | 0.91 | SLC34A2 (0.55) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL6002461 | 0.91 | SLC34A2 (0.52) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL39722 | 0.90 | SLC34A2 (0.57) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL40075 | 0.89 | SLC34A2 (0.52) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL19579971 | 0.89 | SLC34A2 (0.50) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL39860 | 0.88 | SLC34A2 (0.53) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL45535 | 0.88 | SLC34A2 (0.64) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL19580033 | 0.88 | SLC34A2 (0.51) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL19579940 | 0.88 | SLC34A2 (0.58) | SLC34A2BRAFRAF1USP2TLR9 | |
| SCHEMBL15432502 | 0.88 | SLC34A2 (0.52) | SLC34A2BRAFRAF1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |