SCHEMBL19583192

SCHEMBL19583192

C=CC(=O)OCC(O)COc1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
ALDH1A1 P00352 4/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 4/20 0.47
POLB P06746 2/20 0.46
LMNA P02545 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 2/20 0.46
USP2 O75604 1/20 0.46
MAPK1 P28482 2/20 0.45
THRB P10828 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14173310 0.88 CYP1A2 (0.50) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL818941 0.88 CYP1A2 (0.50) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL2128155 0.88 CYP1A2 (0.50) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL2127664 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AKDM4ETDP1
SCHEMBL21436768 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL10609343 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL819519 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL819190 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL14173321 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL14173328 0.85 CYP1A2 (0.48) CYP1A2ALDH1A1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226545-B2 Micro injectable, low chromatic aberration intraocular lens materials BENZ RESEARCH AND DEVELOPMENT CORP (US) 2025-02-18 US disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
CN-110891618-B Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2023-01-03 CN disclosed
US-20220249737-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2022-08-11 US disclosed
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
CN-109475660-B Hydrophobic intraocular lenses 宾视研发公司 2022-03-22 CN disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
US-10899862-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-26 US disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
US-20200330643-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2020-10-22 US disclosed
CN-110891618-A Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2020-03-17 CN disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
EP-3458118-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2019-03-27 EP disclosed
US-10196470-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2019-02-05 US disclosed
US-20180334520-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 US disclosed
WO-2018213240-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 WO disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed