Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958502 | 1.00 | ABCB1 (0.77) | ABCB1ABCG2PDE4BMEN1MAPT | |
| SCHEMBL1959112 | 0.90 | ABCB1 (0.79) | ABCB1ABCG2PDE4BMEN1MAPT | |
| SCHEMBL1959109 | 0.90 | ABCB1 (0.79) | ABCB1ABCG2PDE4BMEN1MAPT | |
| SCHEMBL1959409 | 0.89 | ABCB1 (0.77) | ABCB1ABCG2PDE4BMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1958060 | 0.89 | ABCB1 (0.77) | ABCB1ABCG2PDE4BMEN1MAPT | |
| SCHEMBL1959412 | 0.89 | ABCB1 (0.77) | ABCB1ABCG2PDE4BMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1958058 | 0.89 | ABCB1 (0.77) | ABCB1ABCG2PDE4BMEN1MAPT | |
| SCHEMBL1960400 | 0.88 | ABCB1 (0.76) | ABCB1ABCG2PDE4BMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1957193 | 0.88 | ABCB1 (0.76) | ABCB1ABCG2PDE4BMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1957190 | 0.88 | ABCB1 (0.76) | ABCB1ABCG2PDE4BMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697742-B2 | BCRP/ABCG2 inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-04-15 | — | — | US | claimed |
| EP-2332905-B1 | BCRP/ABCG2 Inhibitor | YAKULT HONSHA KK (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-8697742-B2 | BCRP/ABCG2 inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-04-15 | — | — | US | disclosed |
| EP-2332905-A1 | BCRP/ABCG3 Inhibitor | Kabushiki Kaisha Yakult Honsha (JP) | 2011-06-15 | — | — | EP | disclosed |
| EP-1864972-A1 | BCRP/ABCG2 INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2007-12-12 | — | — | EP | disclosed |