Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959056 | 1.00 | ABCB1 (0.59) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1958788 | 0.99 | ABCB1 (0.58) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1958785 | 0.99 | ABCB1 (0.58) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL1956912 | 0.96 | ABCB1 (0.57) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL1956914 | 0.96 | ABCB1 (0.57) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1959096 | 0.95 | ABCB1 (0.56) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1959099 | 0.95 | ABCB1 (0.56) | ABCB1ABCG2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL1959560 | 0.88 | ABCB1 (0.59) | ABCB1ABCG2ALDH1A1PSMD14APAF1 | |
| SCHEMBL1959563 | 0.88 | ABCB1 (0.59) | ABCB1ABCG2ALDH1A1PSMD14APAF1 | |
| Hydrochloric Acid SCHEMBL1958467 | 0.87 | ABCB1 (0.59) | ABCB1ABCG2PSMD14APAF1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332905-B1 | BCRP/ABCG2 Inhibitor | YAKULT HONSHA KK (JP) | 2017-03-01 | — | — | EP | claimed |
| EP-2332905-A1 | BCRP/ABCG3 Inhibitor | Kabushiki Kaisha Yakult Honsha (JP) | 2011-06-15 | — | — | EP | claimed |
| US-20090253656-A1 | BCRP/ABCG2 INHIBITOR | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-10-08 | — | — | US | claimed |
| EP-1864972-A1 | BCRP/ABCG2 INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2007-12-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253656-A1 | BCRP/ABCG2 INHIBITOR | ABCC1, ABCB1, BRCA1 | ABCB1 2/4885ABCG2 7/4885TMEM97 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.