Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221519 | 1.00 | MDM2 (0.87) | MDM2TP53 | |
| SCHEMBL2590159 | 0.93 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL223761 | 0.93 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL10299794 | 0.93 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL1957377 | 0.93 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL222159 | 0.93 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL222121 | 0.90 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL1955928 | 0.90 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL222673 | 0.90 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL223646 | 0.90 | MDM2 (1.00) | MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067185-A1 | SPIROINDOLINONE PYRROLIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |