Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551650 | 0.95 | MEN1 (0.48) | MEN1KMT2ABACE1TACR1OPRD1 | |
| SCHEMBL15878183 | 0.89 | MEN1 (0.44) | MEN1KMT2ABACE1TACR1OPRD1 | |
| SCHEMBL15797644 | 0.89 | MEN1 (0.44) | MEN1KMT2ABACE1TACR1OPRD1 | |
| SCHEMBL15796942 | 0.89 | MEN1 (0.44) | MEN1KMT2ABACE1TACR1OPRD1 | |
| SCHEMBL7507956 | 0.86 | MEN1 (0.49) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL2206561 | 0.85 | MEN1 (0.47) | MEN1KMT2ABACE1TACR1OPRD1 | |
| SCHEMBL3104656 | 0.82 | MEN1 (0.50) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL14638218 | 0.82 | MEN1 (0.43) | MEN1KMT2ABACE1STSP2RX7 | |
| SCHEMBL14650130 | 0.82 | MEN1 (0.43) | MEN1KMT2ABACE1STSP2RX7 | |
| SCHEMBL21009793 | 0.82 | MEN1 (0.46) | MEN1KMT2ABACE1TACR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507211-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011068560-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2010065824-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |