Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12690294 | 0.82 | MAP3K14 (0.47) | MAP3K14PIK3CDPIK3R1 | |
| SCHEMBL12690421 | 0.81 | MAP3K14 (0.53) | MAP3K14 | |
| SCHEMBL12539558 | 0.80 | HTR2A (0.38) | PIK3CD | |
| SCHEMBL12539358 | 0.73 | PIK3CD (0.58) | PIK3CD | |
| SCHEMBL15192690 | 0.70 | MAP3K14 (0.59) | MAP3K14PIK3CDPIK3R1 | |
| SCHEMBL15192368 | 0.69 | MAP3K14 (0.63) | MAP3K14 | |
| SCHEMBL16029438 | 0.68 | PIK3CA (0.41) | MAP3K14PIK3CDPIK3R1 | |
| SCHEMBL19594278 | 0.67 | PIK3CD (0.38) | MAP3K14PIK3CDPIK3R1 | |
| SCHEMBL15194210 | 0.67 | MAP3K14 (0.56) | MAP3K14PIK3CDPIK3R1 | |
| SCHEMBL12693530 | 0.67 | PIK3CA (0.40) | MAP3K14PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688891-B1 | BENZOXAZEPIN COMPOUNDS SELECTIVE FOR PI3K P110 DELTA AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2017-11-15 | — | — | EP | disclosed |