⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370004 | 0.74 | — | — | |
| SCHEMBL18869864 | 0.74 | — | — | |
| SCHEMBL18666429 | 0.74 | — | — | |
| SCHEMBL2766558 | 0.74 | — | — | |
| SCHEMBL23917930 | 0.69 | — | — | |
| SCHEMBL20844126 | 0.69 | — | — | |
| SCHEMBL20844113 | 0.67 | — | — | |
| SCHEMBL14220751 | 0.65 | TDP1 (0.32) | — | |
| SCHEMBL18509964 | 0.65 | TDP1 (0.32) | — | |
| SCHEMBL19159056 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205778-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-3741357-A1 | AMPHIPHILIC POLYMER SYSTEMS | Universitätsspital Basel (CH) | 2020-11-25 | — | — | EP | disclosed |
| WO-2020200284-A1 | PREPARATION METHOD FOR TRICYCLIC COMPOUND AND USE OF SAME IN FIELD OF MEDICINE | 上海华汇拓医药科技有限公司 | 2020-10-08 | — | — | WO | disclosed |
| EP-3632944-A1 | POLYMERS AND DNA COPOLYMER COATINGS | Illumina Cambridge Limited (GB) | 2020-04-08 | — | — | EP | disclosed |
| EP-2961747-B1 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-11-15 | — | — | EP | disclosed |