Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29189739 | 0.97 | TSHR (0.42) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL2601778 | 0.97 | TSHR (0.42) | TSHROPRM1LMNADNM1THRB | |
| Hydrochloric Acid SCHEMBL5480968 | 0.97 | TSHR (0.42) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL12939814 | 0.97 | TSHR (0.42) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL8644486 | 0.97 | TSHR (0.42) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL29525101 | 0.95 | TSHR (0.40) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL7158134 | 0.92 | TSHR (0.42) | TSHROPRM1LMNADNM1 | |
| SCHEMBL3671291 | 0.92 | — | — | |
| SCHEMBL1131040 | 0.89 | TSHR (0.48) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL10154809 | 0.87 | TSHR (0.34) | TSHROPRM1LMNADNM1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881397-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-04-12 | — | — | CN | claimed |
| CN-105732426-B | A kind of synthetic method of the phenylbutyronitrile compound of 4 oxo 4 | 温州大学 | 2018-01-23 | — | — | CN | claimed |
| CN-105732426-A | Synthesis method of 4-oxo-4-phenyl nitrile compound | 温州大学 | 2016-07-06 | — | — | CN | claimed |
| EP-4499634-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | Nikang Therapeutics, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-117881397-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117835976-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117642401-A | Naphthyridine derivatives as ATR inhibitors and methods of preparing same | 微境生物医药科技(上海)有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117500802-A | LACTIVICIN compounds, their preparation and their use as antibacterial agents | 费多拉制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117255684-A | Quinazolinamine derivatives as KRAS inhibitors | 尼坎治疗公司 | 2023-12-19 | — | — | CN | disclosed |
| WO-2023192801-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2007143847-A1 | SPIROTROPANE COMPOUNDS | VIROCHEM PHARMA INC. (CA) | 2007-12-21 | — | — | WO | disclosed |
| EP-1824853-A1 | NOVEL SPIROTROPANE COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY | Virochem Pharma Inc. (CA) | 2007-08-29 | — | — | EP | disclosed |
| CN-1882596-A | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1871218-A | Isopentyl carboxanilides for combating undesired micro-organisms | BAYER CROPSCIENCE AG (DE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1871221-A | N-substituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1812714-A | Active substance combinations based on trifluorobutenyl compounds and exhibiting nematicidal and insecticidal properties | BAYER CROPSCIENCE AG (DE) | 2006-08-02 | — | — | CN | disclosed |
| WO-2006060918-A1 | NOVEL SPIROTROPANE COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY | VIROCHEM PHARMA INC. (CA) | 2006-06-15 | — | — | WO | disclosed |
| US-5834499-A | TREATING GASTROINTESTINAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0545892-A1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1993-06-09 | — | — | EP | disclosed |