Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | APP | P05067 | 6/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090371 | 0.88 | MAPT (0.59) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL13501922 | 0.87 | MAPT (0.58) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL31684374 | 0.87 | MAPT (0.58) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL15043913 | 0.87 | MAPT (0.58) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL13245825 | 0.86 | MAPT (0.66) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL13903812 | 0.86 | NPC1 (0.71) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL16203529 | 0.85 | NPC1 (0.64) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL29466163 | 0.85 | MAPT (0.72) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL13903820 | 0.85 | MAPT (0.72) | MAPTAPPSNCATP53KDM4E | |
| SCHEMBL17402113 | 0.85 | MAPT (0.64) | MAPTAPPSNCATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326114-A1 | COGNITIVE FUNCTION | GEORGETOWN UNIVERSITY | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326114-A1 | COGNITIVE FUNCTION | CHAT, FABP7, BCHE | MAPT 50/4885APP 133/4885SNCA 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.