SCHEMBL1960059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1958292	0.93	ATR (0.38)	ATRFFAR4SMN1; SMN2NPC1CASP3
	SCHEMBL1960876	0.86	ATR (0.42)	ATRFFAR4NPC1RAB9AMEN1
	SCHEMBL1956347	0.81	ATR (0.41)	ATRFFAR4SCN9AMEN1KMT2A
	SCHEMBL1958499	0.80	GCK (0.44)	ATRFFAR4
	SCHEMBL1957037	0.79	KDM4E (0.39)	ATRMEN1KMT2AKDM4E
	SCHEMBL1958651	0.76	ATR (0.44)	ATRFFAR4SCN9AMEN1KMT2A
	SCHEMBL1959280	0.76	FFAR4 (0.44)	FFAR4SMN1; SMN2NPC1CASP3RAB9A
	SCHEMBL25407994	0.76	SCN9A (0.40)	ATRSCN9AFPR2CYP1A2SLC6A3
	SCHEMBL38661717	0.74	ATR (0.49)	ATRSMN1; SMN2NPC1CASP3RAB9A
	SCHEMBL38663529	0.74	ATR (0.49)	ATRSMN1; SMN2NPC1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.