Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 15/20 | 0.86 |
| ▸ | RPS6KA2 | Q15349 | 10/20 | 0.86 |
| ▸ | RPS6KA1 | Q15418 | 3/20 | 0.86 |
| ▸ | RPS6KA6 | Q9UK32 | 3/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252934 | 0.93 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252937 | 0.91 | RPS6KA3 (0.85) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19601069 | 0.89 | RPS6KA3 (0.81) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19601066 | 0.87 | RPS6KA3 (0.76) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL26931306 | 0.87 | RPS6KA2 (0.68) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252941 | 0.86 | RPS6KA3 (0.84) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19278647 | 0.85 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252896 | 0.85 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| Hydrochloric Acid SCHEMBL29477399 | 0.85 | RPS6KA3 (0.98) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| Hydrochloric Acid SCHEMBL19252861 | 0.85 | RPS6KA3 (0.98) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327501-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | PHOENIX MOLECULAR DESIGNS (CA) | 2017-11-16 | — | — | US | disclosed |
| US-20170327501-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | PHOENIX MOLECULAR DESIGNS (CA) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327501-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | RPS6KA2, RPS6KA5, RPS6KA1 | RPS6KA3 4/4885RPS6KA2 1/4885RPS6KA1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.