Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL1961434 | 0.92 | SLC22A6 (0.44) | OR51E2LMNATET2KDM2AKDM4A | |
| SCHEMBL27465091 | 0.80 | TET2 (0.56) | LMNAEGLN1ALKBH5SUCNR1TET2 | |
| SCHEMBL93977 | 0.78 | OR51E2 (0.50) | OR51E2LMNA | |
| SCHEMBL4985589 | 0.76 | OR51E2 (0.48) | OR51E2LMNA | |
| SCHEMBL6249794 | 0.76 | OR51E2 (0.48) | OR51E2LMNA | |
| Water SCHEMBL22418485 | 0.76 | OR51E2 (0.55) | OR51E2LMNA | |
| SCHEMBL4183255 | 0.76 | OR51E2 (0.44) | OR51E2LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL236695 | 0.75 | OR51E2 (0.42) | OR51E2LMNA | |
| SCHEMBL265908 | 0.74 | OR51E2 (0.46) | OR51E2 | |
| Ethylene Glycol SCHEMBL3837465 | 0.74 | OR51E2 (0.46) | OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255934-A1 | COMPOSITIONS FOR GOLF EQUIPMENT | ACUSHNET COMPANY | 2010-10-07 | — | — | US | claimed |
| US-7635742-B2 | Crosslinking polyurethanes | RHODIA CHIMIE (FR) | 2009-12-22 | — | — | US | claimed |
| US-20070173348-A1 | Compositions for Golf Equipment | ACUSHNET COMPANY | 2007-07-26 | — | — | US | claimed |
| US-20110130222-A1 | COMPOSITIONS FOR GOLF EQUIPMENT | ACUSHNET COMPANY | 2011-06-02 | — | — | US | disclosed |
| US-20100255934-A1 | COMPOSITIONS FOR GOLF EQUIPMENT | ACUSHNET COMPANY | 2010-10-07 | — | — | US | disclosed |
| US-20100240469-A1 | COMPOSITIONS FOR GOLF EQUIPMENT | ACUSHNET COMPANY | 2010-09-23 | — | — | US | disclosed |
| US-7709590-B2 | Compositions for golf equipment | ACUSHNET COMPANY (US) | 2010-05-04 | — | — | US | disclosed |
| US-7635742-B2 | Crosslinking polyurethanes | RHODIA CHIMIE (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7550549-B2 | Compositions for golf equipment | ACUSHNET COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080188326-A1 | Compositions for Golf Equipment | ACUSHNET COMPANY | 2008-08-07 | — | — | US | disclosed |
| US-20080125247-A1 | Compositions for Golf Equipment | ACUSHNET COMPANY | 2008-05-29 | — | — | US | disclosed |
| US-20040220356-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220377-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220378-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220373-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220376-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220371-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040220357-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |
| US-20040073046-A1 | Modified isocyanates | RHODIA CHIMIE (FR) | 2004-04-15 | — | — | US | disclosed |
| US-20030050424-A1 | Modified isocyanates | RHODIA CHIMIE (FR) | 2003-03-13 | — | — | US | disclosed |