Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26748819 | 0.88 | ACACB (0.54) | ACACBGPR119 | |
| SCHEMBL20805558 | 0.85 | ACACB (0.42) | ACACBGPR119 | |
| SCHEMBL26748822 | 0.77 | PANK3 (0.44) | GPR119 | |
| SCHEMBL20805438 | 0.74 | HRH3 (0.41) | ACACB | |
| SCHEMBL23015397 | 0.73 | PANK3 (0.48) | GPR119 | |
| SCHEMBL26581344 | 0.72 | ACACB (0.51) | ACACBGPR119 | |
| SCHEMBL19606449 | 0.71 | ACACB (0.50) | ACACBGPR119 | |
| SCHEMBL24654370 | 0.69 | ACACB (0.48) | ACACBGPR119 | |
| SCHEMBL18591817 | 0.68 | EGLN2 (0.40) | ACACBGPR119 | |
| SCHEMBL23046563 | 0.67 | GRM4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |