SCHEMBL19610430

SCHEMBL19610430

CCCCOc1nc(N)c2nc(OC)n(CCCCCCC3CCNCC3)c2n1.CCI

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.63
TLR8 Q9NR97 5/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1842120 0.97 TLR7 (0.66) TLR7TLR8
SCHEMBL1842653 0.97 TLR7 (0.66) TLR7TLR8
SCHEMBL1842286 0.96 TLR7 (0.66) TLR7TLR8
SCHEMBL1839331 0.94 TLR7 (0.65) TLR7TLR8
SCHEMBL1838481 0.91 TLR7 (0.65) TLR7TLR8
SCHEMBL1841044 0.87 TLR7 (0.67) TLR7TLR8
SCHEMBL1840277 0.86 TLR7 (0.52) TLR7TLR8
SCHEMBL1843309 0.86 TLR7 (0.68) TLR7TLR8
SCHEMBL1841036 0.85 TLR7 (0.53) TLR7TLR8
SCHEMBL2199628 0.85 TLR7 (0.65) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246030-A1 NOVEL ADENINE DERIVATIVES GlaxoSmithKline LLC (US) 2017-11-22 EP disclosed