Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841956 | 1.00 | TLR7 (0.46) | TLR7TLR8NPY1R | |
| SCHEMBL1842486 | 0.95 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL1837719 | 0.94 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL19610412 | 0.94 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL1843919 | 0.89 | TLR7 (0.57) | TLR7TLR8 | |
| SCHEMBL1841874 | 0.84 | TLR7 (0.41) | TLR7TLR8 | |
| SCHEMBL2198489 | 0.84 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL1843049 | 0.84 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL2198836 | 0.84 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL1840210 | 0.84 | TLR7 (0.62) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246030-A1 | NOVEL ADENINE DERIVATIVES | GlaxoSmithKline LLC (US) | 2017-11-22 | — | — | EP | disclosed |