Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.66 |
| ▸ | PDE4A | P27815 | 12/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PDE1A | P54750 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529448 | 0.89 | PDE4B (0.78) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL5583359 | 0.80 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL595819 | 0.80 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2530321 | 0.78 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL11993084 | 0.77 | PDE4B (0.78) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2530713 | 0.76 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2531912 | 0.76 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2529550 | 0.76 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2526209 | 0.75 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL30571023 | 0.75 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |