Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.83 |
| ▸ | ABL1 | P00519 | 2/20 | 0.82 |
| ▸ | BCR | P11274 | 1/20 | 0.82 |
| ▸ | FYN | P06241 | 3/20 | 0.75 |
| ▸ | EGFR | P00533 | 1/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.70 |
| ▸ | ABL2 | P42684 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184168 | 0.91 | SRC (1.00) | SRCABL1BCRFYNEGFR | |
| SCHEMBL5198196 | 0.91 | SRC (1.00) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL19610540 | 0.89 | SRC (0.80) | SRCABL1BCRFYNEGFR | |
| SCHEMBL19610518 | 0.89 | SRC (0.82) | SRCABL1BCRFYNEGFR | |
| SCHEMBL19610585 | 0.87 | SRC (0.77) | SRCABL1BCRFYNEGFR | |
| SCHEMBL934766 | 0.86 | SRC (1.00) | SRCABL1BCRFYNEGFR | |
| SCHEMBL6384840 | 0.85 | SRC (0.85) | SRCABL1BCRFYNEGFR | |
| SCHEMBL6181489 | 0.85 | SRC (0.84) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5201099 | 0.84 | SRC (1.00) | SRCABL1BCRFYNEGFR | |
| SCHEMBL27527072 | 0.84 | SRC (0.76) | SRCABL1BCREGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198756-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-23 | — | — | WO | claimed |
| EP-3246028-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-22 | — | — | EP | claimed |
| WO-2017198756-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246028-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-22 | — | — | EP | disclosed |