Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.60 |
| ▸ | KIT | P10721 | 9/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18101235 | 0.96 | KDR (0.56) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL589205 | 0.92 | KDR (0.68) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL29516846 | 0.85 | KDR (0.67) | KDRKITPDGFRAHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL29516748 | 0.84 | KDR (0.66) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL11953494 | 0.84 | KDR (0.66) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL23587599 | 0.83 | KDR (0.56) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL14347685 | 0.81 | KDR (0.67) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL20729864 | 0.79 | KDR (0.65) | KDRKITPDGFRAHDAC1HDAC6 | |
| SCHEMBL13849112 | 0.79 | KDR (0.65) | KDRKITPDGFRAHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL30817650 | 0.78 | KDR (0.64) | KDRKITPDGFRAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120197019-A1 | COMPOSITIONS AND PROCESSES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-08-02 | — | — | US | disclosed |
| US-20120197019-A1 | COMPOSITIONS AND PROCESSES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-08-02 | — | — | US | disclosed |
| WO-2011069053-A1 | PROCESS FOR THE PREPARATION OF PAZOPANIP HCL AND CRYSTALLINE FORMS OF PAZOPANIB HCL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011050159-A1 | COMPOSITIONS AND PROCESSES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197019-A1 | COMPOSITIONS AND PROCESSES | PIK3CA, PNP, PIK3CB | KDR 9/4885KIT 1655/4885PDGFRA 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.