Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.89 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL1961302 | 1.00 | FABP3 (0.89) | FABP3TERTMAPTBLMHSD17B10 | |
| Palmitoleic Acid SCHEMBL23466354 | 0.96 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL387380 | 0.96 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL387377 | 0.96 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL1204866 | 0.94 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL1203905 | 0.94 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL28162246 | 0.94 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL1203908 | 0.94 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL1204868 | 0.94 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL233567 | 0.94 | FABP3 (1.00) | FABP3TERTMAPTBLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150203752-A1 | Colloidal Nanocrystals Ensembles with Narrow Linewidth Band Gap Photoluminescence and Methods of Synthesizing Colloidal Semiconductor Nanocrystals | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2015-07-23 | — | — | US | disclosed |
| US-8932489-B2 | Colloidal nanocrystal ensembles with narrow linewidth band gap photoluminescence and methods of synthesizing colloidal semiconductor nanocrystals | NATIONAL RESEARCH COUNCIL OF CANADA. (CA) | 2015-01-13 | — | — | US | disclosed |
| US-20110140046-A1 | Colloidal Nanocrystal Ensembles with Narrow LInewidth Band Gap Photoluminescence and Methods of Synthesizing Colloidal Semiconductor Nanocrystals | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-06-16 | — | — | US | disclosed |
| WO-2010017634-A1 | COLLOIDAL NANOCRYSTAL ENSEMBLES WITH NARROW LINEWIDTH BAND GAP PHOTOLUMINESCENCE AND METHODS OF SYNTHESIZING COLLOIDAL SEMICONDUCTOR NANOCRYSTALS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-02-18 | — | — | WO | disclosed |