SCHEMBL1961533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1961094	0.91	HDAC6 (0.41)	HDAC6GCKHPGDSEPHX2NAMPT
	SCHEMBL1964344	0.90	HDAC6 (0.39)	HDAC6GCKEPHX2NAMPTSYK
	SCHEMBL27873099	0.89	GCK (0.40)	HDAC6GCKCA2CA1EPHX2
	SCHEMBL1961534	0.89	EPHX2 (0.43)	HDAC6EPHX2NAMPTMAPK8RIPK1
	SCHEMBL1961944	0.86	GCK (0.55)	HDAC6GCK
	SCHEMBL1959934	0.82	GCK (0.40)	GCKEPHX2SYKCTSLCTSB
	SCHEMBL1959970	0.82	GCK (0.40)	GCKEPHX2SYKCTSLCTSB
	SCHEMBL1963036	0.78	GCK (0.56)	HDAC6GCKEPHX2
	SCHEMBL1960236	0.78	GCK (0.56)	HDAC6GCKEPHX2
	SCHEMBL1961948	0.77	GCK (0.53)	GCKEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.