Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12275427 | 0.90 | MEN1 (0.31) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL46040 | 0.88 | MAPK1 (0.32) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL37220 | 0.87 | MEN1 (0.32) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL38046 | 0.87 | MEN1 (0.32) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL12072063 | 0.86 | MEN1 (0.31) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL46162 | 0.85 | MEN1 (0.31) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL45939 | 0.84 | MEN1 (0.30) | MEN1MAPK1KMT2A | |
| SCHEMBL12072065 | 0.84 | POLB (0.33) | POLBMEN1MAPK1KMT2A | |
| SCHEMBL17703627 | 0.83 | POLB (0.31) | POLBMEN1KMT2A | |
| SCHEMBL37415 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| EP-2507213-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067131-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067131-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | DDT, PKD2, PKD1 | POLB 4601/4885MEN1 1097/4885MAPK1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.