SCHEMBL196162

SCHEMBL196162

CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(Cc1ccccc1C#N)c(=O)n2C

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196161 1.00 DPP4 (0.83) DPP4
SCHEMBL4667656 0.94 DPP4 (0.90) DPP4
SCHEMBL4668939 0.94 DPP4 (0.90) DPP4
SCHEMBL24311071 0.92 DPP4 (0.82) DPP4
SCHEMBL3554935 0.92 DPP4 (0.70) DPP4
SCHEMBL3554943 0.92 DPP4 (0.70) DPP4
SCHEMBL3971579 0.91 DPP4 (0.77) DPP4
SCHEMBL3971578 0.91 DPP4 (0.77) DPP4
SCHEMBL556850 0.91 DPP4 (0.84) DPP4
SCHEMBL685384 0.91 DPP4 (0.84) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250312456-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY BOEHRINGER INGELHEIM INT (DE) 2025-10-09 US claimed
US-20220323434-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY BOEHRINGER INGELHEIM INT (DE) 2022-10-13 US claimed
EP-3939577-A1 PHARMACEUTICAL COMPOSITION COMPRISING A GLUCOPYRANOSYL-SUBSTITUTED BENZENE DERIVATIVE Boehringer Ingelheim International GmbH (DE) 2022-01-19 EP claimed
CN-112656945-A Treatment of diabetes in patients unsuited for metformin therapy 勃林格殷格翰国际有限公司 2021-04-16 CN claimed
US-20210093633-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY BOEHRINGER INGELHEIM INT (DE) 2021-04-01 US claimed
EP-3626238-A1 DPP-4 INHIBITORS FOR USE FOR THE TREATMENT OF WOUND HEALING IN DIABETIC PATIENTS Boehringer Ingelheim International GmbH (DE) 2020-03-25 EP claimed
US-20190105321-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY BOEHRINGER INGELHEIM INT (DE) 2019-04-11 US claimed
EP-3348263-A1 DPP-IV INHIBITORS FOR USE IN THE TREATMENT OF NAFLD Boehringer Ingelheim International GmbH (DE) 2018-07-18 EP claimed
EP-2119717-B1 8-[3-amino-piperidin-1-yl]-xanthins, their production and utilisation as DPP IV inhibitors BOEHRINGER INGELHEIM INT (DE) 2018-01-17 EP claimed
EP-3106156-A1 PHARMACEUTICAL COMPOSITION COMPRISING A GLUCOPYRANOSYL-SUBSTITUTED BENZENE DERIVATIVE Boehringer Ingelheim International GmbH (DE) 2016-12-21 EP claimed
EP-2187879-A1 PHARMACEUTICAL COMPOSITION COMPRISING A GLUCOPYRANOSYL-SUBSTITUTED BENZENE DERIVATIVE Boehringer Ingelheim International GmbH (DE) 2010-05-26 EP claimed
EP-2187966-A1 PHARMACEUTICAL COMPOSITION COMPRISING A SGLT2 INHIBITOR IN COMBINATION WITH A DPP-IV INHIBITOR Boehringer Ingelheim International GmbH (DE) 2010-05-26 EP claimed
WO-2010043688-A1 TREATMENT FOR DIABETES IN PATIENTS WITH INSUFFICIENT GLYCEMIC CONTROL DESPITE THERAPY WITH AN ORAL OR NON-ORAL ANTIDIABETIC DRUG BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-22 WO claimed
WO-2010029089-A2 COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND RELATED CONDITIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-03-18 WO claimed
WO-2010018217-A2 ORGANIC COMPOUNDS FOR WOUND HEALING BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-02-18 WO claimed
WO-2010015664-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-02-11 WO claimed
WO-2009147125-A1 DPP-IV INHIBITORS FOR USE IN THE TREATMENT OF NAFLD BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-12-10 WO claimed
WO-2009022007-A1 PHARMACEUTICAL COMPOSITION COMPRISING A GLUCOPYRANOSYL-SUBSTITUTED BENZENE DERIVATIVE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-19 WO claimed
WO-2009022010-A1 PHARMACEUTICAL COMPOSITION COMPRISING A SGLT2 INHIBITOR IN COMBINATION WITH A DPP-IV INHIBITOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-19 WO claimed
WO-2009022008-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PYRAZOLE-O-GLUCOSIDE DERIVATIVE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210093633-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY DPP4, DPP3, DPP7 DPP4 1/4885
US-20250312456-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY DPP4, DPP3, DPP7 DPP4 1/4885
US-20220323434-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY DPP4, DPP3, DPP7 DPP4 1/4885
US-20190105321-A1 TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY DPP4, DPP3, DPP7 DPP4 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.