Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL639674 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL1164966 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL19307797 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL1164859 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL19617523 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL17062522 | 1.00 | CHRM2 (0.52) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL20958534 | 0.91 | CHRM2 (0.44) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL20958537 | 0.91 | CHRM2 (0.44) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL1165401 | 0.91 | CHRM2 (0.44) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL1165403 | 0.91 | CHRM2 (0.44) | CHRM2CHRM1CHRM3LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458449-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |